US Politics | The true story of how nurse Amy Loughren unraveled murders of Charles Cullen who killed up to 400 across US hospitals

CHARLES Cullen has been regarded as one of, if not the most, prolific serial killers in the history of the United States \- but a new series is focusing instead on the woman who unraveled his murders. Academy Award winners Eddie Redmayne and Jessica Chastain star in the new Netflix film The Good Nurse, which focuses on the story of nurse Amy Loughren. Charles Cullen admitted to killing 29 patientsGetty Images - Getty Amy Loughren is the nurse who got Cullen to confess to his crimesGetty Images Loughren worked as a nurse at Somerset Medical CenterWikipedia Over 16 years, Cullen admittedly killed 29 people \- but there are estimates that he murdered as many as 400 patients. Cullen tended to kill his patients through the use of a combination of intravenous fluids, which often included mixes of insulin, epinephrine, and digoxin. He moved around from hospital to hospital, always leaving before the administration could grow suspicious as his patients died of medication overdoses. Cullen finally came under scrutiny at the last hospital that employed him. READ MORE CRIME STORIES THIEF CRACKDOWN Thousands of thieves to be fitted with GPS tags in push to cut reoffending SHIFTING THE BLAME Quinton Simon's dad makes bombshell claim about toddler's mom It was there that his former friend, Loughren, a fellow nurse, agreed to work with the police to implicate him. Loughren wore a wire and talked to Cullen long enough for police to gather the evidence needed to pin him for the crimes. On December 12, 2003, Cullen was brought in for one first-degree murder and one attempted murder, and the next day, he shocked officers with a confession.  Cullen ultimately admitted to 29 murders; however, he also pre-mixed IV bags so that other nurses and doctors were technically killing patients unknowingly. 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The two also drew from the 2013 book entitled The Good Nurse: A True Story of Medicine, Madness and Murder, by Charles Graeber. Instead of focusing on Cullen alone, the two chose to focus on Loughren and asking questions of the US healthcare system. "I saw the potential of doing a serial killer in a way that we had never seen it before, where we wouldn't be seduced by why is he doing this or how damaged is he as a person, but take a step back and look at why and how would we allow for this to go on," Lindholm told the AP. "He's not, in my mind, Hannibal Lecter. It's not this brilliant mind. ...It's a fairly simple guy doing a fairly simple thing, but a system allowing it." CHASTAIN WORKED WITH LOUGHREN To step into Loughren's shoes in the film, Chastain spoke to the mom, who was living in upstate New York but working at Somerset Hospital in New Jersey. "She worked nights so her daughters felt like she was a stay-at-home mom. That's what she kept saying, that her kids saw her when they were awake," Chastain said. "The idea that this woman would risk her health in order to provide for her children and also risk her comfort by not getting the sleep she needed, it told me so much about who she was and what she was capable of." Chastain also took from Loughren's other lived experiences, including working as a nurse with a heart condition. The actress jogged around set before filming scenes in order to elevate her heart rate, the AP reports. While filming, Chastain also wore an earpiece that played a heart beat that could speed up during a scene. "This woman 'Loughren ' just wasn't recognized for what she did," Wilson-Cairns said. "People don't think of ordinary women as these kind of heroes. They're not on screens, they're not in the media, they're not in books enough. ...To see the real Amy finally be recognized in a small way for what she did – which is save countless lives – I thought: That's not a bad way to spend a decade. I'd do that again." Read More on The US Sun DECISION TIME Serena Williams' stepmom's bid to save childhood home to be decided in days JUSTICE AT LAST Parade killer found guilty of murder of 6 after crashing car into crowd The Good Nurse will be available on Netflix worldwide beginning on Wednesday, October 26, 2022. The description for the film on Netflix reads: "Suspicious that her colleague is responsible for a series of mysterious patient deaths, a nurse risks her own life to uncover the truth in this gripping thriller based on true events."

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